![]() Rarely, more serious side effects, such as damage to a tendon, nerve injury, or allergic reaction, may occur. ![]() The most common side effects are swelling in the affected area, or bleeding, bruising, and pain at the injection site. Most people need one or two injections in the affected joint, but some people may need up to three injections to straighten or nearly straighten the finger. This weakens the tight bands and may allow your doctor to then stretch the tightened area and straighten your finger. If your fingers are already bent, collagenase ( Xiaflex), a mixture of enzymes that help dissolve the tough tissue, may be injected into the affected area by your doctor.
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